Here is my XI to play the West Indies in the first test match at Lords. I am assuming here that neither Vaughan or Pietersen is fit and that Trescothick (still a centrally contracted player by the way) would rather smack county attacks around.

Andrew Strauss *
Alastair Cook
Ian Bell
Paul Collingwood
Rob Key
Andrew Flintoff
Matt Prior +
Steve Harmison
Monty Panesar
Matthew Hoggard
Jimmy Anderson

Have gone for Strauss as captain, he knows Lords and is less likely to get drunk and fall in the Thames, Prior as wicketkeeper (consistency of selection is crucial), and Rob Key to amply fill the Pietersen shaped gap. Big Rob has scored lots of test runs at Lords against the Windies in 2004, and is a good stop gap.